Harvard University researchers used single-cell sequencing to identify a protein expressed uniquely by insulin-producing beta cells created from stem cells in the laboratory.By targeting the protein and adding a physical enrichment method developed by collaborators at Semma Therapeutics, the purity of beta cells improved from 30 to 80%.Improved control over the beta cell production process will allow researchers to refine cell therapy for patients with type 1 diabetes.
Source: EurekaAlert, https://www.eurekalert.org