Keeping things in proportion: Lem2 necessary for nuclear scaling

A research team led by Hiroshima University found that inner nuclear membrane protein Lem2, backed up by endoplasmic reticulum protein Lnp1, acts as a valve to control the flow of the membrane into and out of the nuclear envelope. The researchers showed that by controlling membrane flow, Lem2 forms part of a regulatory system responsible for nuclear scaling, maintaining a constant nucleus to cell volume ratio.
Source: EurekaAlert,