NMR structure of a key anticoagulant protein may help prevent thrombosis

A group of researchers from Brazil and the United States describes for the first time the structure of Ixolaris, an important anticoagulant protein found in tick saliva, and its interaction with Factor Xa, a key enzyme in the process of blood clotting. The results may benefit cancer patients, of whom approximately 20% will develop thrombosis during the disease progression.
Source: EurekaAlert, https://www.eurekalert.org