Novel and rapid device opens new doors for Parkinson's disease diagnostics

Researchers from Osaka University developed a new device that can measure levels of α-synuclein aggregates in cerebrospinal fluid. This ‘HANdai Amyloid Burst Inducer’ device amplifies and detects misfolded α-synuclein using ultrasonication. The use of ultrasonication greatly reduced the assay processing time compared with existing methods. Seeding activity of α-synuclein was correlated with disease severity and radiographic examinations.
Source: EurekaAlert,