Potential new therapy takes aim at a lethal esophageal cancer's glutamine addiction

Medical University of South Carolina investigators have exploited a metabolic quirk of certain cancers known as glutamine addiction to identify a potential new therapy for esophageal cancer. After characterizing the pathway involved in cancer progression, they tested a new combination treatment in both cells and animal models, with promising results. The next step is to secure funding to bring the new combination regimen to clinical trial. Their findings are reported in Nature Communications.
Source: EurekaAlert, https://www.eurekalert.org