Studying the function of liver cancer genes in mini-organs

Researchers from the Hubrecht Institute developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer. Using this method, they have found that mutations in BAP1, a gene commonly mutated in liver cancer, changes the behavior of the cells, which may make them more likely to be invasive. Their results were published in Cell Stem Cell.
Source: EurekaAlert,