Why Hodgkin's lymphoma cells grow uncontrollably

Although classical Hodgkin’s lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery. A team at the Max Delbrück Center led by Professor Claus Scheidereit has now identified an important signaling molecule in the biology of this lymphoma: LTA. It helps the cancer to grow unimpeded – for example, by activating genes for immune checkpoint ligands that protect tumor cells from the body’s built-in defense system.
Source: EurekaAlert, https://www.eurekalert.org